2021.05.17 Our recent work was accepted by Nano Today
In this work, the nanoparticles (sCND) were prepared by high temperature carbonization of food-derived materials which owned uniform small size, good water-dispersity, glioma-targeted accumulation, etc. Moreover, sCND could interfere the energy metabolism of tumor cells, inhibit their growth and proliferation, and improve the cancer sensitivity to chemotherapy. In addition, sCND had long-term excellent biosafety including low cytotoxicity, no apparent hematotoxicity and tissue damages. This work explored a simple method to prepare the biosafety of therapeutic nanomaterials and provided a theoretical basis about the great potential of nanotechnology for clinical application in cancer treatment. This work was mainly accomplished by Prof. Yi Wang and Ph.D. Taotao Huo.
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